ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0015.10-22 | Prevention | ESPEYB15

10.22 Effect of oral insulin on prevention of diabetes in relatives of patients with T1DM: a randomized clinical trial

Writing Committee for the T1DM TrialNet Oral Insulin Study Group , JP Krischer , DA Schatz , B Bundy , JS Skyler , CJ Greenbaum

To read the full abstract: JAMA. 2017;318:1891-1902Insulin is one of the autoantigens involved in the pathogenesis of T1DM. Therefore several trials with insulin given orally, nasal or subcutaneous have been conducted to prevent the development of T1DM in genetically high risk populations. This trial design built on the results of DPT-1 and included further investigations related to first phase...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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